129 | id == 129
129 | category_id == 14
129 | category_order == 12
129 | category_name == Nutrition
129 | category_color == #C47AC0
129 | slug == SLC30A8-nutrition-zinc
129 | title == How A Zinc Gene Affects Blood Sugar (SLC30A8)
129 | meta_description == SLC30A8 plays a key role in transporting zinc in the body, but certain genetic variants may increase the risk of diabetes.
129 | summary == <p style="text-align:justify"><strong>The SLC30A8 gene plays an important role in the transport of zinc and the production of insulin. Certain variants of SLC30A8 can impair this function, which may increase the risk of developing type 2 diabetes. Find out how this gene works and who may be affected.</strong></p>
129 | overall_score_text == Zinc Score (Based On SLC30A8 Gene)
129 | image == https://sd-selfdecode-assets-prod.s3.amazonaws.com/blog/background/SLC30A8--Nutrients-Zinc.jpg
129 | author_id == 8
129 | author_name == Mathew Eng
129 | author_title == PharmD
129 | author_order == 40
129 | author_photo == https://sd-selfdecode-assets-prod.s3.amazonaws.com/blog/author-photo/Mathew.jpg
129 | author_intro == <p><strong>Mathew received his PharmD from the University of Hawaii and an undergraduate degree in Biology from the University of Washington.</strong></p>    <p>Mathew is a licensed pharmacist with clinical experience in oncology, infectious disease, and diabetes management. He has a passion for personalized patient care and believes that education is essential to living a healthy life. His goal is to motivate individuals to find ways to manage their chronic conditions.</p>
129 | reviewer == None
129 | medical_reviewer_id == 11
129 | medical_reviewer_name == Puya Yazdi
129 | medical_reviewer_title == MD
129 | publish_date == 2020
129 | publish_date == 3
129 | publish_date == 24
129 | avg_rating == 5.0
129 | tags_id == 127
129 | tags_name == Diabetes Type 2
129 | tags_id == 139
129 | tags_name == Insulin
129 | tags_id == 92
129 | tags_name == Magnesium
129 | tags_id == 340
129 | tags_name == SLC30A8 Gene
129 | tags_id == 341
129 | tags_name == Zinc
129 | permissions_favorite == False
129 | permissions_rate == False
129 | content_article == <h2><strong>The <em>SLC30A8</em> Gene</strong></h2> <p><span style="font-weight: 400;">The </span><a href="../../gene/slc30a8/"><em><span style="font-weight: 400;">SLC30A8</span></em></a><span style="font-weight: 400;"> gene encodes a protein called </span><strong>zinc transporter 8</strong><span style="font-weight: 400;"> (</span><strong>ZNT8</strong><span style="font-weight: 400;">).</span></p> <p><span style="font-weight: 400;">As the name suggests, the ZNT8 protein is responsible for transporting </span><a href="https://selfhacked.com/blog/literally-everything-wanted-know-zinc-backed-science/"><span style="font-weight: 400;">zinc</span></a><span style="font-weight: 400;"> around the body, primarily in beta-cells of the pancreas [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/23979673"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Zinc is an essential mineral that plays many key roles in the body, including the production and secretion of </span><a href="https://selfhacked.com/blog/insulin-101/"><span style="font-weight: 400;">insulin</span></a><span style="font-weight: 400;"> from beta-cells [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/23979673"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Studies have found that certain variants of the </span><em><span style="font-weight: 400;">SLC30A8</span></em><span style="font-weight: 400;"> gene may disrupt zinc transport, potentially leading to imbalances in zinc levels and increasing the risk of type 2 diabetes [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/25287711"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Check out these links for more information on the </span><a href="https://selfhacked.com/blog/literally-everything-wanted-know-zinc-backed-science/"><span style="font-weight: 400;">health effects of zinc</span></a><span style="font-weight: 400;"> and the </span><a href="https://selfhacked.com/blog/insulin-101/"><span style="font-weight: 400;">function of insulin</span></a><span style="font-weight: 400;">.</span></p> <h2><strong>How Do <em>SLC30A8</em> Variants Cause Problems?</strong></h2> <p><span style="font-weight: 400;">Research suggests that certain variants of </span><em><span style="font-weight: 400;">SLC30A8</span></em><span style="font-weight: 400;"> may decrease the transport activity of ZNT8, potentially leading to lower zinc levels near the beta-cells of the pancreas [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/25287711"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Zinc levels are usually very high in beta-cells because zinc is required for the production of insulin [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/25287711"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Genetic variants that decrease zinc transport activity may ultimately lead to lower insulin levels, higher </span><a href="https://www.selfhacked.com/blog/top-tips-for-fixing-insulin-resistance/"><span style="font-weight: 400;">insulin resistance</span></a><span style="font-weight: 400;">, and a higher risk of </span><a href="https://selfhacked.com/blog/glucose/"><span style="font-weight: 400;">type 2 diabetes</span></a><span style="font-weight: 400;"> [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/25287711"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/26832344"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <h2><strong>Who Is Affected?</strong></h2> <h3><strong>The rs13266634 Variant</strong></h3> <p><span style="font-weight: 400;">One of the most studied </span><em><span style="font-weight: 400;">SLC30A8</span></em><span style="font-weight: 400;"> variants is the SNP </span><strong>rs13266634</strong><span style="font-weight: 400;">. Research suggests that the &lsquo;C&rsquo; allele is strongly linked to impaired zinc transport and type 2 diabetes (T2DM) [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/25287711"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/26832344"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/30319545"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">For instance, a systematic review of 39 studies including data from over 165,000 individuals found that the &lsquo;C&rsquo; allele was associated with a higher risk of T2DM in Asian and European populations [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/26214053"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">According to the review, those carrying one &lsquo;C&rsquo; allele had a 16.5% higher risk of T2DM and those carrying two &lsquo;C&rsquo; alleles had a 33% higher risk compared to those carrying no risk alleles [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/26214053"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Other large studies and reviews have found the same association in Chinese, Uygur, African, Japanese, French, Saudi, and Russian populations [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/30485937"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/30319545"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/26837367"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/26832344"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/18162508"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/18210030"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/25501231"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/20873210"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400; background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">The &lsquo;C&rsquo; allele of rs13266634 is associated with impaired zinc transport and a higher risk of type 2 diabetes in many different European and Asian populations.</span></p> <h3><strong>The rs11558471 Variant</strong></h3> <p><span style="font-weight: 400;">Variations in </span><strong>rs11558471 </strong><span style="font-weight: 400;">may also affect zinc transport activity and the risk of type 2 diabetes.</span></p> <p><span style="font-weight: 400;">Two studies, both including nearly 3,000 Chinese participants, concluded that the &lsquo;A&rsquo; allele of rs11558471 is strongly associated with a higher risk of T2DM [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/20550665"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/22653633"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">According to one of these Chinese studies, T2DM patients were almost twice as likely to have the &lsquo;AA&rsquo; genotype compared to those without T2DM [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/22653633"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Similar associations between the &lsquo;A&rsquo; allele and T2DM risk have been found in Punjabi and Malay populations [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176767/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365519/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400; background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">The &lsquo;A&rsquo; allele of rs11558471 is associated with impaired zinc transport and a higher risk of type 2 diabetes in Chinese, Punjabi, and Malay populations.</span></p> <h3><strong>The rs3802177 Variant</strong></h3> <p><span style="font-weight: 400;">Based on a study of nearly 3,000 Chinese individuals, each copy of the &lsquo;G&rsquo; allele of rs3802177 is associated with a 17% higher risk of type 2 diabetes [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494677/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">The &lsquo;G&rsquo; allele is also linked to impaired zinc transport and a higher risk of T2DM in Japanese and European groups, according to other research [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/18477659"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400; background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">The &lsquo;G&rsquo; allele of rs3802177 is associated with impaired zinc transport and a higher risk of type 2 diabetes in Chinese, Japanese, and European populations.</span></p> <h3><strong>Conflicting Evidence</strong></h3> <p><span style="font-weight: 400;">Not all research of </span><em><span style="font-weight: 400;">SLC30A8</span></em><span style="font-weight: 400;"> has been straightforward. Several studies have revealed inconclusive and sometimes contradictory results.</span></p> <p><span style="font-weight: 400;">For example, one study looking at isolated human pancreas cells found that the risk allele of rs13266634 does </span><strong>not</strong><span style="font-weight: 400;"> alter insulin secretion or expression of </span><em><span style="font-weight: 400;">SLC30A8 </span></em><span style="font-weight: 400;">[</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/20138556"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Another study of pancreas cells suggests that the risk allele of rs13266634 results in </span><em><span style="font-weight: 400;">higher</span></em><span style="font-weight: 400;"> levels of zinc in the beta-cells, despite being linked to T2DM [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428289/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">To make matters even more confusing, rare variants of </span><em><span style="font-weight: 400;">SLC30A8</span></em><span style="font-weight: 400;"> that completely inactivate the zinc transporter actually produce a protective effect against T2DM [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/24584071"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">These conflicting studies show that our understanding of how </span><em><span style="font-weight: 400;">SLC30A8</span></em><span style="font-weight: 400;"> affects zinc levels and diabetes is incomplete and that more research is needed.</span></p> <h2><strong>Your <em>SLC30A8</em> Results for Zinc Levels &amp; Diabetes</strong></h2> <p><em><span style="font-weight: 400;">You can see your genotypes for SLC30A8 in the table below. However, keep in mind that these associations are based on studies from certain ethnic populations &mdash; so you should interpret your results with caution if you are not descended from one of these specific groups!</span></em></p> <p>*2100944345551805*</p> <h3><strong>SNP Summary and Table</strong></h3> <p><strong>Primary SNPs:&nbsp;</strong></p> <p><strong>SLC30A8 rs13266634</strong></p> <ul> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;T&rsquo; = Associated with normal zinc transport&nbsp;</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;C&rsquo; = Associated with impaired zinc transport and a higher risk of type 2 diabetes</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">This association has been found in European and Asian populations</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">About 57% of people worldwide have the &lsquo;CC&rsquo; genotype (highest risk)</span></li> </ul> <p><strong>SLC30A8 rs11558471</strong></p> <ul> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;G&rsquo; = Associated with normal zinc transport&nbsp;</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;A&rsquo; = Associated with impaired zinc transport and a higher risk of type 2 diabetes</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">This association has been found in Chinese, Punjabi, and Malay populations</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">About 57% of people worldwide have the &lsquo;AA&rsquo; genotype (highest risk)</span></li> </ul> <p><strong>SLC30A8 rs3802177</strong></p> <ul> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;A&rsquo; = Associated with normal zinc transport</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;G&rsquo; = Associated with impaired zinc transport and a higher risk of type 2 diabetes</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">This association has been found in Chinese, Japanese, and European populations</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">About 57% of people worldwide have the &lsquo;GG&rsquo; genotype (highest risk)</span></li> </ul> <p>*9197880613295701*</p> <h2><strong>Recommendations for Zinc Levels &amp; Diabetes</strong></h2> <p><em><span style="font-weight: 400;">Talk to your doctor before implementing any of the following strategies. There may be unexpected interactions with your current medications or health conditions.&nbsp;</span></em></p> <p><em><span style="font-weight: 400;">None of these recommendations should ever be used to replace any of the treatments or medications that your doctor gives you.</span></em></p> <p>*6403118629334235*</p> <p><span style="font-weight: 400;">As highlighted throughout this article, zinc plays a crucial role in </span><a href="https://selfhacked.com/blog/insulin-101/"><span style="font-weight: 400;">insulin</span></a><span style="font-weight: 400;"> control and the development of diabetes.</span></p> <p><span style="font-weight: 400;">A number of studies have found that zinc supplementation can help control </span><a href="https://selfhacked.com/blog/glucose/"><span style="font-weight: 400;">blood sugar</span></a><span style="font-weight: 400;"> (</span><a href="https://selfhacked.com/blog/glucose/"><span style="font-weight: 400;">glucose</span></a><span style="font-weight: 400;">) and improve insulin levels [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407731/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/28138861"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">There is also some evidence that zinc and magnesium have direct effects on the </span><em><span style="font-weight: 400;">SLC30A8</span></em><span style="font-weight: 400;"> gene, which may further help control diabetes [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161318/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713023/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">For more information, check out our articles on </span><a href="https://selfhacked.com/blog/literally-everything-wanted-know-zinc-backed-science/"><span style="font-weight: 400;">zinc</span></a><span style="font-weight: 400;"> and </span><a href="https://selfhacked.com/blog/21-proven-science-based-reasons-magnesium-amazing-including-drawbacks/"><span style="font-weight: 400;">magnesium</span></a><span style="font-weight: 400;">.</span></p> <h3><strong>Diet</strong></h3> <h4><strong>Foods High In Zinc</strong></h4> <p><a href="https://selfhacked.com/blog/literally-everything-wanted-know-zinc-backed-science/"><span style="font-weight: 400;">Zinc</span></a><span style="font-weight: 400;"> is an essential mineral, meaning that the body gets the zinc it needs through diet or supplements [</span><a href="https://ods.od.nih.gov/factsheets/Zinc-Consumer/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Generally speaking, the recommended daily intake of zinc is 8 mg for women and 11 mg for men. However, there may be benefits to higher zinc levels [</span><a href="https://ods.od.nih.gov/factsheets/Zinc-Consumer/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">One study including over 46,000 participants who had an average daily zinc intake of about 14 mg found that higher zinc intake is correlated with lower blood glucose levels [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161318/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Some foods that are rich in zinc include [</span><a href="https://ods.od.nih.gov/factsheets/Zinc-Consumer/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]:</span></p> <ul> <li style="font-weight: 400;"><span style="font-weight: 400;">Oysters</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Red meat</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Poultry</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Seafood</span></li> </ul> <p><span style="font-weight: 400;">Just be aware that it is possible to consume too much zinc, which can have negative health effects. Zinc intake should not exceed 40 mg each day unless directed by a doctor [</span><a href="https://ods.od.nih.gov/factsheets/Zinc-Consumer/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <h4><strong>Foods High in Magnesium</strong></h4> <p><span style="font-weight: 400;">Research shows that </span><a href="https://selfhacked.com/blog/21-proven-science-based-reasons-magnesium-amazing-including-drawbacks/"><span style="font-weight: 400;">magnesium</span></a><span style="font-weight: 400;"> may have similar effects as zinc when it comes to controlling blood glucose and insulin levels [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549665/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">The recommended daily intake of magnesium is about 320 mg for women and 420 mg for men. However, once again, higher intake of magnesium may provide additional benefits [</span><a href="https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713023/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">A study of over 52,6000 people suggests that each 100 mg increment of magnesium intake may reduce the risk of type 2 diabetes by about 14% [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713023/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Some great sources of magnesium include [</span><a href="https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]:</span></p> <ul> <li style="font-weight: 400;"><span style="font-weight: 400;">Almonds, cashews, peanuts, and pumpkin seeds</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Green leafy vegetables, such as spinach</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Black beans and edamame</span></li> </ul> <h3><strong>Supplements</strong></h3> <h4><strong>Zinc Supplementation</strong></h4> <p><span style="font-weight: 400;">If you can&rsquo;t get enough zinc from food sources, supplements may also be an option.</span></p> <p><span style="font-weight: 400;">Zinc supplements are available in many different forms, including zinc gluconate, zinc sulfate, and zinc acetate. Zinc is also a common component in many multivitamin products [</span><a href="https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">These different supplement forms contain different amounts of zinc, but it&rsquo;s not clear if one form is better than the other [</span><a href="https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">One study suggests that zinc supplementation may be particularly effective at counteracting the glucose-raising effects caused by the risk allele (&lsquo;A&rsquo;) of rs11558471 [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161318/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p>
129 | content_snp_table_2100944345551805_key == 2100944345551805
129 | content_snp_table_2100944345551805_blur == True
129 | content_snp_table_2100944345551805_hidden == False
129 | content_learn_more_9197880613295701_key == 9197880613295701
129 | content_learn_more_9197880613295701_blur == True
129 | content_learn_more_9197880613295701_hidden == False
129 | content_learn_more_9197880613295701_text == Based on the variants we looked at, your SLC30A8 genotype is somewhat associated with impaired zinc transport and a higher risk of type 2 diabetes. However, this doesn't necessarily reflect your overall risk — just one gene related to it. Diet and supplements may help. Keep scrolling to find out more.
129 | content_recommendation_6403118629334235_key == 6403118629334235
129 | content_recommendation_6403118629334235_blur == True
129 | content_recommendation_6403118629334235_hidden == False
rsIDs = rs11558471,rs13266634,rs3802177
rsStatus = rs11558471,SLC30A8,chr8,117173494,A,G,,,8,37,HET
rsStatus = rs13266634,SLC30A8,chr8,117172544,C,A,T,,42,0,Normal
rsStatus = rs3802177,SLC30A8,chr8,117172786,G,A,,,5,27,HET
