194 | id == 194
194 | category_id == 16
194 | category_order == 13
194 | category_name == Gut Health
194 | category_color == #C47AC0
194 | slug == ABO-gastritis
194 | title == What Does Blood Type Have to Do with Gastritis? (ABO)
194 | meta_description == ABO is the major gene that determines blood group. Can it affect your susceptibility to stomach inflammation? Find out here.
194 | summary == <p><strong>ABO is the major gene that determines blood group. Can it affect your immune response and susceptibility to stomach inflammation? Read on to find out.</strong></p>
194 | overall_score_text == Gastritis Score (based on ABO)
194 | image == https://sd-selfdecode-assets-prod.s3.amazonaws.com/blog/background/ABO--Gut-Inflammation-Gastritis---all-chips.jpg
194 | author_id == 1
194 | author_name == Jasmine Foster
194 | author_title == BSc, BEd
194 | author_order == 36
194 | author_photo == https://sd-selfdecode-assets-prod.s3.amazonaws.com/blog/author-photo/Jasmine.jpg
194 | author_intro == <p><strong>Jasmine received her BS from McGill University and her BEd from Vancouver Island University.</strong></p>    <p>Jasmine loves helping people understand their brains and bodies, a passion that grew out of her dual background in biology and education. From the chem lab to the classroom, everyone has the right to learn and make informed decisions about their health.</p>
194 | reviewer == None
194 | medical_reviewer_id == 11
194 | medical_reviewer_name == Puya Yazdi
194 | medical_reviewer_title == MD
194 | publish_date == 2020
194 | publish_date == 5
194 | publish_date == 18
194 | avg_rating == 4.2
194 | tags_id == 451
194 | tags_name == ABO Gene
194 | tags_id == 453
194 | tags_name == Blood Group
194 | tags_id == 452
194 | tags_name == Blood Type
194 | tags_id == 450
194 | tags_name == Gastritis
194 | tags_id == 194
194 | tags_name == Gut Health
194 | tags_id == 308
194 | tags_name == Gut Inflammation
194 | tags_id == 432
194 | tags_name == H. pylori
194 | tags_id == 246
194 | tags_name == Probiotics
194 | permissions_favorite == False
194 | permissions_rate == False
194 | content_article == <p><em><span style="font-weight: 400;">This article is for informational purposes only. None of the information here should be taken as medical advice. If you suspect you may have digestive issues, seek medical help. </span></em><em><span style="font-weight: 400;">Keep in mind that these results are based on association studies, which are correlative and aren&rsquo;t necessarily causative. Any single genetic variant will typically contribute only a small proportion to the overall risk of the condition, and non-genetic factors play a large role in developing a condition as well. Therefore, just because you have one of these genotypes does not necessarily mean you are at an increased risk of developing this condition!</span></em></p> <h2><span style="font-weight: 400;">What is ABO?</span></h2> <p><span style="font-weight: 400;">ABO is the major gene that determines blood type in humans. Several variants combine to determine blood type, the major ones being rs8176719, rs8176746, and rs8176747. Using these SNPs, researchers can identify whether someone has an A, B, AB, or O blood type [</span><a href="https://ghr.nlm.nih.gov/gene/ABO"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">ABO blood groups may produce resistance or susceptibility to various diseases and disorders. For example, people with an O blood type are </span><a href="https://selfhacked.com/blog/blood-types-and-coronavirus/"><span style="font-weight: 400;">somewhat protected from many infections</span></a><span style="font-weight: 400;"> and types of cancer compared to people with type A, B, or AB blood types [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827391/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061611/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ahajournals.org/doi/10.1161/ATVBAHA.119.313658"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://cebp.aacrjournals.org/content/20/8/1665.long"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Generally speaking, O blood types appear to be linked with better health outcomes than B, and B blood types better than A, though there are exceptions to this rule [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796869/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://cmr.asm.org/content/28/3/801"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <h2><span style="font-weight: 400;">ABO &amp; Gut Inflammation</span></h2> <p><span style="font-weight: 400;">The O blood types (O+ and O-) appear to produce more intense (and often more effective) responses to pathogenic bacteria like </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;"> in the gut [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190290/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">The </span><a href="https://selfhacked.com/blog/how-to-increase-and-decrease-white-blood-cells/"><span style="font-weight: 400;">white blood cells</span></a><span style="font-weight: 400;"> of people with O blood types are more likely to move into the gut lining and produce inflammatory signals in response to </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;">. Researchers have pointed to this phenomenon as the reason why O blood types are associated with lower rates of infection, but higher rates of gastritis and ulcers [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190290/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">The reason for the difference in white blood cell behavior is not completely certain. However, some research suggests that the A, B, and O blood antigens may change the way white blood cells bind to potential threats; type O leukocytes, for example, bound to pieces of </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;"> much more effectively than type A or type B leukocytes [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/10753728/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;"><span style="font-weight: 400;">People in the O blood group may have white blood cells that can bind more effectively to </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;"> and produce a more intense inflammatory response.</span></span></p> <h3><span style="font-weight: 400;">What is Gastritis?</span></h3> <p><span style="font-weight: 400;">Gastritis is a condition characterized by inflammation of the stomach lining. It may be acute (sudden and short-term) or chronic (developing slowly and long-term). One type of gastritis called erosive gastritis breaks down the lining of the stomach, sometimes leading to </span><a href="https://selfhacked.com/blog/ulcers/"><span style="font-weight: 400;">ulcers</span></a><span style="font-weight: 400;">. Another type, called atrophic gastritis, causes a loss of glandular tissue in the lining of the stomach, often replaced by scar tissue; this type is often caused by an autoimmune reaction [</span><a href="https://www.niddk.nih.gov/health-information/digestive-diseases/gastritis-gastropathy/definition-facts"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://rarediseases.info.nih.gov/diseases/10310/autoimmune-atrophic-gastritis"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Gastritis can have a number of causes. These include</span> <a href="https://selfhacked.com/blog/h-pylori-part-1/"><em><span style="font-weight: 400;">H. pylori</span></em></a><span style="font-weight: 400;"> infection, long-term NSAID use, alcohol abuse, cocaine use, or autoimmune disease. Severe injuries, burns, sepsis, and some drugs can also cause acute erosive gastritis [</span><a href="https://www.niddk.nih.gov/health-information/digestive-diseases/gastritis-gastropathy/definition-facts"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]</span></p> <p><em>H. pylori</em> is the most common cause of gastritis, and about 35% of the US population is infected with this bacteria [<a href="https://www.niddk.nih.gov/health-information/digestive-diseases/gastritis-gastropathy/definition-facts">R</a>].</p> <h2><span style="font-weight: 400;">ABO Variants &amp; Gastritis</span></h2> <p><span style="font-weight: 400;">At least two studies have found that people with a genetic marker for type &lsquo;B&rsquo; blood have lower rates of gastritis in response to </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;"> infection. The &lsquo;T&rsquo; allele of rs8176746 (which signifies B group blood) is associated with reduced rates of gastritis, while the &lsquo;G&rsquo; allele of rs8176746 (which signifies A group blood) is associated with increased rates of gastritis [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/21680535"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://cebp.aacrjournals.org/content/20/8/1665.long"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">When compared to O type blood, B type blood may reduce the incidence of gastritis and A type blood may increase the incidence of gastritis [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/21680535"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://cebp.aacrjournals.org/content/20/8/1665.long"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/12673421"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Inheritance of blood groups is surprisingly complex, relying on the interaction of rs8176746, rs8176747, and rs8176719 (a deletion mutation that signifies O type). If you know your blood type, it is more reliable to refer to that rather than to infer based on these SNPs.</span></p> <p><span style="font-weight: 400;">In summary:</span></p> <ul> <li style="font-weight: 400;"><span style="font-weight: 400;">Type B: Lowest likelihood of gastritis</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Type O: Medium likelihood of gastritis</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Type A: Highest likelihood of gastritis</span></li> </ul> <p><span style="font-weight: 400; background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">The variant that indicates B blood group (rs8176746-T) is associated with lower rates of gastritis, while the variant that indicates A blood group (rs8176746-G) is associated with higher rates of gastritis.</span></p> <h2><span style="font-weight: 400;">Your ABO Results for Gastritis</span></h2> <p>*5294149381350868*</p> <h3><span style="font-weight: 400;">SNP Summary and Table</span></h3> <p><strong>ABO rs8176746</strong></p> <ul> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;G&rsquo; = Associated with lack of B blood group and possibly increased rates of gastritis</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;T&rsquo; = Associated with presence of B blood group and possibly reduced rates of gastritis</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Only about 27% of all people worldwide have at least one copy of the &lsquo;T&rsquo; allele.</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">The &lsquo;T&rsquo; allele (and the B blood group) are significantly more common in South Asian populations (40%) and significantly less common in European (16%) and American (9%) populations.</span></li> </ul> <p><strong>ABO rs8176747</strong></p> <ul> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;G&rsquo; = Associated with lack of A blood group and possibly reduced rates of gastritis</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;C&rsquo; = Associated with presence of A blood group and possibly increased rates of gastritis</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Only about 27% of all people worldwide have at least one copy of the &lsquo;G&rsquo; allele.</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">The distribution of alleles at rs8176747 is very similar to that of rs8176746.</span></li> </ul> <p><span style="font-weight: 400;">Genotypes at these two SNPs and a deletion mutation, rs8176719, combine to determine blood type. If you want to do a deeper dive, here&rsquo;s a quick guide to get started:</span></p> <ul> <li style="font-weight: 400;"><span style="font-weight: 400;">rs8176746-GG + rs8176747-CC without the deletion at rs8176719 produces type A blood</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">rs8176746-GT + rs8176747-CG without the deletion at rs8176719 produces type AB blood</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">rs8176746-TT + rs8176747-GG without the deletion at rs8176719 produces type B blood</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">One copy of the deletion at rs8176719 replaces one allele with an &lsquo;O&rsquo; allele, producing either type A or type B blood (refer to other two SNPs).</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Two copies of the deletion at rs8176719 replaces both alleles with &lsquo;O&rsquo; alleles, producing type O blood.</span></li> </ul> <p>*3170488853950128*</p> <h2><span style="font-weight: 400;">Recommendations for Reducing Stomach Inflammation</span></h2> <p><em><span style="font-weight: 400;">You may try the complementary approaches listed below if you and your doctor determine that they could be appropriate for you. Discuss the strategies listed here with your doctor. Remember that none of them should ever be done in place of what your doctor recommends or prescribes.</span></em></p> <p>*4527620247477926*</p> <p><span style="font-weight: 400;">There is no known advantage or disadvantage to increasing or decreasing the quantity of A or B antigens produced in the blood. These recommendations will therefore focus on strategies that have been found to both control the immune response, inhibit </span><em><span style="font-weight: 400;">H. pylori,</span></em><span style="font-weight: 400;"> and reduce the incidence or severity of gastritis.&nbsp;</span></p> <p><span style="font-weight: 400;">For a more complete list of complementary strategies that improved gastritis in clinical studies, </span><a href="https://selfhacked.com/blog/gastritis/"><span style="font-weight: 400;">check out this post</span></a><span style="font-weight: 400;">.</span></p> <h3><span style="font-weight: 400;">Diet</span></h3> <h4><span style="font-weight: 400;">A Note on Blood Group Diets</span></h4> <p><span style="font-weight: 400;">Some people believe that certain diets are better for different blood types. The so-called &ldquo;blood type diet&rdquo; or &ldquo;blood group diet&rdquo; was popularized by P. J. D&rsquo;Adamo in his 1996 book </span><em><span style="font-weight: 400;">Eat Right For Your Type</span></em><span style="font-weight: 400;">. However, while these specialized diets have been associated with positive health outcomes, their benefits were not specific to any single blood type, and none has been found to decrease the incidence of gastritis [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893150/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <h4><span style="font-weight: 400;">Eliminate Proinflammatory Foods</span></h4> <p><span style="font-weight: 400;">Certain dietary components may trigger an inflammatory response in people who are predisposed to chronic inflammation [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276397/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047770/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Doctors may recommend avoiding certain foods that may increase the intensity of the immune response and aggravate gastric inflammation. It is important to follow any dietary restrictions your doctor recommends; if you do not receive dietary guidance, you may want to ask them about the foods on this list:</span></p> <ul> <li style="font-weight: 400;"><span style="font-weight: 400;">Soft drinks: soft drinks and other carbonated beverages are also believed to stimulate acid secretion and are therefore often on the list of things to avoid if you have gastritis [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/2072799"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743227/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Sweets &amp; simple sugars: some evidence suggests that simple carbohydrates may stimulate the production of stomach acid and worsen outcomes in gastric inflammation [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/29729504"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Very fatty food: some doctors may advise against fatty meats and cheeses, and you may be advised to cut deep fried foods entirely [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743227/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></li> </ul> <p><span style="font-weight: 400; background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">Certain foods may trigger inflammation in people who are predisposed to gastritis; cutting these out, or at least reducing intake, may improve outcomes.</span></p> <h4><span style="font-weight: 400;">Fermented Foods</span></h4> <p><span style="font-weight: 400;">Certain fermented beverages &ndash; especially wine, beer, and fermented milk &ndash; have produced promising clinical results in supporting </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;"> and gastritis treatment, likely because they are a natural source of probiotic bacteria [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958626/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/19447974"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">In a cross-sectional study of over 10,000 people in England, moderate consumption of wine and beer was found to be somewhat protective against </span><em><span style="font-weight: 400;">H. pylori </span></em><span style="font-weight: 400;">infection. The authors suggested that moderate wine and beer consumption could produce an environment in the stomach that is hostile to </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;">, thereby making it easier to eradicate the bacteria [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/12425543"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">However, another study found that alcohol consumption was positively associated with </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;"> infection, suggesting that a component of wine and beer other than alcohol could be responsible for their apparent benefit [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/19808941"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Fermented dairy products such as yogurt and </span><a href="https://selfhacked.com/blog/kefir/"><span style="font-weight: 400;">kefir</span></a><span style="font-weight: 400;"> were also found to be protective against </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;"> infection. Furthermore, the addition of yogurt to conventional therapy improved eradication rates in one trial of 347 patients [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958626/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714294/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/18665934/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Some authors have suggested that other fermented foods could protect against </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;">, but that our poor understanding of specific ethnic fermented foods around the world is a major obstacle to using them in a clinical setting [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958626/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;"><span style="font-weight: 400;">Fermented foods and drinks are a natural source of probiotic bacteria that may help outcompete </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;"> and prevent gastritis.</span></span></p> <h4><span style="font-weight: 400;">Broccoli Sprouts &amp; Brassica Vegetables</span></h4> <p><a href="https://selfhacked.com/blog/panacea-benefits-broccoli-sprouts-sulforaphane/"><span style="font-weight: 400;">Sulforaphane</span></a><span style="font-weight: 400;">, a compound found in broccoli and </span><a href="https://selfhacked.com/blog/panacea-benefits-broccoli-sprouts-sulforaphane/"><span style="font-weight: 400;">broccoli sprouts</span></a><span style="font-weight: 400;">, may inhibit the growth of </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;"> and thereby prevent </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;">-associated gastritis [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047973/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Researchers have suggested that sulforaphane may protect the mucosal membranes of the stomach, which may lead to reduced inflammation [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/19349290"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]. Improved mucosal membrane health may also make it more difficult for</span><em><span style="font-weight: 400;"> H. pylori</span></em><span style="font-weight: 400;"> to colonize the stomach effectively, explaining the reduced rate of colonization found in some studies [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/19349290"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">In asymptomatic patients with confirmed </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;"> infection, eating 70 g/day of broccoli sprouts resulted in a significant decrease of colonization intensity [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047973/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Another study also reported a loss of </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;"> colonization following broccoli sprout treatment in four out of nine test subjects [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465045/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">In type 2 diabetic patients infected with </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;">, broccoli sprouts powder in addition to standard triple therapy showed a considerable improvement in </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;"> eradication, and also showed improved heart health in subjects [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060758/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">In mice,</span><em><span style="font-weight: 400;"> H. pylori </span></em><span style="font-weight: 400;">infections were effectively eliminated by sulforaphane injections [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465045/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">However, a small study with </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;">-colonized humans in Japan was unable to demonstrate an improvement when supplementing broccoli sprouts [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465045/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Other brassica vegetables (cauliflower, swede, headed cabbage, turnip, radish) also contain compounds in the same family as sulforaphane, collectively called isothiocyanates [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047973/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;"><span style="font-weight: 400;">Sulforaphane is a compound found in broccoli sprouts and other brassica vegetables which help eradicate </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;"> and prevent gastritis.</span></span></p> <h3><span style="font-weight: 400;">Supplements</span></h3> <h4><span style="font-weight: 400;">Probiotics</span></h4> <p><span style="font-weight: 400;">A healthy gut flora is in constant communication with our immune systems, suppressing inflammation and sending signals that it is not a threat. Certain probiotic supplements (</span><em><span style="font-weight: 400;">Lactobacillus</span></em><span style="font-weight: 400;"> and </span><em><span style="font-weight: 400;">Bifidobacterium </span></em><span style="font-weight: 400;">species) may help soothe the immune response and reduce the excess information associated with some blood groups [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490534/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><a href="https://selfhacked.com/blog/probiotics-good-bacteria/"><span style="font-weight: 400;">Probiotic</span></a><span style="font-weight: 400;"> supplements are a popular way to support conventional therapies for digestive ailments. In gastritis, they may only be helpful in cases where </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;"> infection is a concern [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906699/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206577/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">According to some researchers, probiotic bacteria compete with </span><em><span style="font-weight: 400;">H. pylori</span></em><span style="font-weight: 400;"> in the digestive tract, possibly making this harmful infection more susceptible to antibiotics and other drugs [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102400/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906699/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590171/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400; background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">Some probiotic bacteria may help soothe the immune response and help manage gastritis.</span></p> <h4><span style="font-weight: 400;">CoQ10</span></h4> <p><span style="font-weight: 400;">Coenzyme Q10 (CoQ10) is an important compound found in every cell in the body. It is a type of coenzyme, which means that it helps other enzymes work more effectively. CoQ10 is mainly located in the membrane of </span><a href="https://selfhacked.com/blog/mitochondria/"><span style="font-weight: 400;">mitochondria</span></a><span style="font-weight: 400;">, where it is used to make energy [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178961/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">The combination of standard antibiotic triple therapy with </span><a href="https://selfhacked.com/blog/coenzyme-q10-ubiquinol/"><span style="font-weight: 400;">CoQ10</span></a><span style="font-weight: 400;"> had a positive effect on the stomach lining inflammation and decreased </span><a href="https://selfhacked.com/blog/oxidative-stress-101/"><span style="font-weight: 400;">oxidative stress</span></a><span style="font-weight: 400;"> in patients with </span><em><span style="font-weight: 400;">H. pylori-</span></em><span style="font-weight: 400;">associated chronic gastritis [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/25854786"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p>
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194 | content_learn_more_3170488853950128_text == Based on the variants we looked at, your ABO gene is associated with average rates of gastritis. However, this doesn't necessarily reflect your overall risk of gastritis, just one gene related to it. Anti-inflammatory dietary choices, probiotic supplements, and stress management strategies may help; keep scrolling to find out more.
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