321 | id == 321
321 | category_id == 20
321 | category_order == 17
321 | category_name == Attention
321 | category_color == #C47AC0
321 | slug == CHRNA4-Attention
321 | title == Could This Gene Impact Your Ability To Navigate? (CHRNA4)
321 | meta_description == CHRNA4 gene variants may be affecting your attention span. Read on to find out more!
321 | summary == <p style="text-align:justify"><strong><em>CHRNA4</em> variants may influence your attention span. Read on to find out the impact these variants may be having on you and what you can do to reduce it!</strong></p>
321 | overall_score_text == Your Attention Score (based on CHRNA4 gene)
321 | image == https://sd-selfdecode-assets-prod.s3.amazonaws.com/blog/background/CHRNA4-Attention.jpg
321 | author_id == 13
321 | author_name == Lewis Cuthbertson
321 | author_title == PhD
321 | author_order == 12
321 | author_photo == https://sd-selfdecode-assets-prod.s3.amazonaws.com/blog/author-photo/Lewis_SelfDecode.jpg
321 | author_intro == <p><strong>Lewis completed his PhD in Molecular Microbiology at Northumbria University (UK).</strong></p>    <p>Lewis spent several years researching the biodiversity of bacterial communities in the Arctic and Antarctic, whilst also performing research for a DNA sequencing service, where he was involved in several health based microbiome studies. This gave him an insight into how the highly diverse and invisible to the naked eye portion of human health, can potentially impact an individual&rsquo;s quality of life, driving his desire to help others understand their own complex health needs through the most current scientific research.<br />  &nbsp;</p>
321 | reviewer == None
321 | medical_reviewer_id == 11
321 | medical_reviewer_name == Puya Yazdi
321 | medical_reviewer_title == MD
321 | publish_date == 2020
321 | publish_date == 9
321 | publish_date == 10
321 | avg_rating == 5.0
321 | tags_id == 237
321 | tags_name == Acetylcholine
321 | tags_id == 56
321 | tags_name == Attention
321 | tags_id == 698
321 | tags_name == CHRNA4 gene
321 | permissions_favorite == False
321 | permissions_rate == False
321 | content_article == <h2 style="text-align: justify;"><span style="font-weight: 400;">Summary</span></h2> <ul style="text-align: justify;"> <li style="font-weight: 400;"><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;"><span style="font-weight: 400;">The </span><em><span style="font-weight: 400;">CHRNA4 </span></em><span style="font-weight: 400;">gene encodes </span><a href="https://selfhacked.com/blog/acetylcholine/"><span style="font-weight: 400;">acetylcholine</span></a><span style="font-weight: 400;"> receptors.</span></span></li> <li style="font-weight: 400;"><span style="font-weight: 400; background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">Variants may lower acetylcholine transport.</span></li> <li style="font-weight: 400;"><span style="font-weight: 400; background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">Lower acetylcholine transport may impair memory storage and therefore attention.</span></li> </ul> <h2 style="text-align: justify;"><em><span style="font-weight: 400;">CHRNA4</span></em><span style="font-weight: 400;"> and Attention</span></h2> <ul style="text-align: justify;"> <li style="font-weight: 400;"><span style="font-weight: 400;">The </span><a href="../../../gene/chrna4/"><em><span style="font-weight: 400;">CHRNA4</span></em></a> <span style="font-weight: 400;">gene encodes </span><a href="https://selfhacked.com/blog/acetylcholine/"><span style="font-weight: 400;">acetylcholine</span></a><span style="font-weight: 400;"> receptors. Acetylcholine is a neurotransmitter.</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Acetylcholine receptors are in part responsible for storing memories and information.</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Variants of </span><em><span style="font-weight: 400;">CHRNA4 </span></em><span style="font-weight: 400;">influence </span><a href="https://selfhacked.com/blog/focus-attention-improve/"><span style="font-weight: 400;">visuospatial attention</span></a><span style="font-weight: 400;"> and gene expression [</span><a href="https://pubmed.ncbi.nlm.nih.gov/27123786/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824511/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/28877969/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Visuospatial attention is the processing of information in your visual field. It may help with navigation.</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Lower gene expression associated with </span><em><span style="font-weight: 400;">CHRNA4 </span></em><span style="font-weight: 400;">variants may reduce neurotransmission, the amount of information stored, and therefore attention.</span></li> </ul> <h2 style="text-align: justify;"><span style="font-weight: 400;">Your</span><em><span style="font-weight: 400;"> CHRNA4</span></em><span style="font-weight: 400;"> Results for Attention</span></h2> <h3 style="text-align: justify;">*3964425135957197*</h3> <h3 style="text-align: justify;"><span style="font-weight: 400;">SNP Table and Summary</span></h3> <p style="text-align: justify;"><strong>[</strong><strong><em>CHRNA4</em></strong><strong>] rs1044396</strong></p> <ul style="text-align: justify;"> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;G&rsquo; = Poorer visuospatial attention/memory [</span><a href="https://pubmed.ncbi.nlm.nih.gov/27123786/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;A&rsquo; = Better visuospatial attention/memory, higher gene expression [</span><a href="https://pubmed.ncbi.nlm.nih.gov/27123786/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824511/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/28877969/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]</span></li> </ul> <p style="text-align: justify;"><span style="font-weight: 400;">*A allele may be associated with protection from video game addiction [</span><a href="https://pubmed.ncbi.nlm.nih.gov/29240768/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]</span></p> <p style="text-align: justify;"><span style="font-weight: 400;">*G allele may be associated with internet addiction [</span><a href="https://www.sciencedirect.com/science/article/pii/B9780128006344000950"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]</span></p> <p style="text-align: justify;"><strong>*3701962783690198*</strong></p> <h2 style="text-align: justify;"><span style="font-weight: 400;">Recommendations for Improving Attention</span></h2> <p style="text-align: justify;"><strong>*5110036747629838*</strong></p> <h3 style="text-align: justify;"><span style="font-weight: 400;">Lifestyle</span></h3> <h4 style="text-align: justify;"><span style="font-weight: 400;">Exercise</span></h4> <ul style="text-align: justify;"> <li style="font-weight: 400;"><span style="font-weight: 400;">Acetylcholine is increased in the brain during exercise, and exercise is also associated with improved cognitive function [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/1483754/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928534/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></li> </ul> <h3 style="text-align: justify;"><span style="font-weight: 400;">Supplements</span></h3> <h4 style="text-align: justify;"><span style="font-weight: 400;">Alpha-GPC</span></h4> <ul style="text-align: justify;"> <li style="font-weight: 400;"><a href="https://selfhacked.com/blog/alpha-gpc/"><span style="font-weight: 400;">Alpha-GPC</span></a><span style="font-weight: 400;"> (alpha-glycerylphosphorylcholine, also known as choline alphoscerate) is known to increase acetylcholine levels [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/8239302"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313098"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/16297435"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Alpha-GPC has also been reported to improve cognitive function [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/11589921"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/29928709"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/12637119"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/18289004"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/23387341"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></li> </ul> <h4 style="text-align: justify;"><span style="font-weight: 400;">Galantamine</span></h4> <ul> <li style="font-weight: 400; text-align: justify;"><span style="font-weight: 400;">Galantamine may also increase acetylcholine levels and improve cognition, by inhibiting enzymes which break acetylcholine down [</span><a href="https://pubmed.ncbi.nlm.nih.gov/15115951/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></li> </ul>
321 | content_snp_table_3964425135957197_key == 3964425135957197
321 | content_snp_table_3964425135957197_blur == True
321 | content_snp_table_3964425135957197_hidden == False
321 | content_learn_more_3701962783690198_key == 3701962783690198
321 | content_learn_more_3701962783690198_blur == True
321 | content_learn_more_3701962783690198_hidden == False
321 | content_learn_more_3701962783690198_text == Based on the variants we looked at, your CHRNA4 gene makes you somewhat more likely to develop a decreased attention span. However, this doesn't necessarily reflect your overall risk of having a poorer attention span; it’s just one gene related to it. Keep scrolling to find out more.
321 | content_recommendation_5110036747629838_key == 5110036747629838
321 | content_recommendation_5110036747629838_blur == True
321 | content_recommendation_5110036747629838_hidden == False
rsIDs = rs1044396
rsStatus = rs1044396,CHRNA4,chr20,63349782,G,A,C,,33,0,Normal
