323 | id == 323
323 | category_id == 20
323 | category_order == 17
323 | category_name == Attention
323 | category_color == #C47AC0
323 | slug == HTR1B-serotonin-ADHD
323 | title == How Serotonin Receptors Impact Attention (HTR1B)
323 | meta_description == The HTR1B gene helps make a serotonin receptor crucial for attention. Click to discover its link with ADHD.
323 | summary == <p style="text-align:justify"><strong>Scientists have found a crucial genetic link between serotonin and attention. Read this post to learn about the HTR1B gene and its role in ADHD.</strong></p>
323 | overall_score_text == Your ADHD Score (Based on HTR1B Gene)
323 | image == https://sd-selfdecode-assets-prod.s3.amazonaws.com/blog/background/HTR1B--HTR2C-ADHD.jpg
323 | author_id == 9
323 | author_name == Aleksa Ristic
323 | author_title == MS (Pharmacy)
323 | author_order == 45
323 | author_photo == https://sd-selfdecode-assets-prod.s3.amazonaws.com/blog/author-photo/Aleksa.jpg
323 | author_intro == <p><strong>Aleksa received his MS in Pharmacy from the University of Belgrade, his master thesis focusing on protein sources in plant-based diets.</strong>&nbsp;&nbsp;</p>    <p>Aleksa is passionate about herbal pharmacy, nutrition, and functional medicine. He found a way to merge his two biggest passions&mdash;writing and health&mdash;and use them for noble purposes. His mission is to bridge the gap between science and everyday life, helping readers improve their health and feel better.</p>
323 | reviewer == None
323 | medical_reviewer_id == 11
323 | medical_reviewer_name == Puya Yazdi
323 | medical_reviewer_title == MD
323 | publish_date == 2020
323 | publish_date == 9
323 | publish_date == 11
323 | avg_rating == 5.0
323 | tags_id == 682
323 | tags_name == 5-HT1B receptor
323 | tags_id == 30
323 | tags_name == ADHD
323 | tags_id == 56
323 | tags_name == Attention
323 | tags_id == 681
323 | tags_name == HTR1B gene
323 | tags_id == 557
323 | tags_name == Omega-3 Fatty Acids
323 | tags_id == 309
323 | tags_name == Serotonin
323 | tags_id == 485
323 | tags_name == Sleep
323 | permissions_favorite == False
323 | permissions_rate == False
323 | content_article == <h2><strong>Summary</strong></h2> <p><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;"><strong>The HTR1B gene helps produce a serotonin receptor, 5-HT1B, with essential roles in attention and mental health.</strong></span><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;"><strong>One HTR1B gene variant is associated with ADHD due to altered serotonin function in the brain.</strong></span><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;"><strong>Specific lifestyle changes and supplements may enhance attention by targeting this variant.</strong></span></p> <h2><strong>The HTR1B Gene in Attention Disorders</strong></h2> <p><span style="font-weight: 400;">The </span><a href="https://www.selfdecode.com/gene/htr1b/?utm_source=seo&amp;#38;utm_medium=selfhacked&amp;#38;utm_campaign=id00002"><span style="font-weight: 400;">HTR1B</span></a><span style="font-weight: 400;"> gene helps produce a </span><a href="https://www.selfhacked.com/blog/how-to-increase-serotonin"><span style="font-weight: 400;">serotonin</span></a><span style="font-weight: 400;"> receptor, 5-HT1B [</span><a href="https://ghr.nlm.nih.gov/gene/HTR1B"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Altered activity of 5-HT1B receptors may contribute to attention disorders, </span><a href="https://selfhacked.com/blog/natural-treatments-depression/"><span style="font-weight: 400;">depression</span></a><span style="font-weight: 400;">, addictive behavior, and more [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919989/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">ADHD is associated with impaired serotonin functions in the brain [</span><a href="https://pubmed.ncbi.nlm.nih.gov/1143984/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/20921119/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <h2><strong>Your HTR1B Results for ADHD</strong></h2> <p>*3118695281585939*</p> <p><strong>HTR1B </strong><a href="../../../snp/rs6296/"><strong>rs6296</strong></a><span style="font-weight: 400;"> [</span><a href="https://pubmed.ncbi.nlm.nih.gov/30074224/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/16197923/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]:</span></p> <ul> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;C&rsquo; - associated with impaired attention and slightly higher odds of ADHD</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;G&rsquo; - not associated with impaired attention</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">This variant may alter brain serotonin levels via the 5-HT1B receptor.</span></li> </ul> <p><strong>Please note</strong><span style="font-weight: 400;">: The quoted studies label the &lsquo;G&rdquo; allele as &lsquo;negative.&rsquo; Unlike SelfDecode, they report on a negative DNA strand, where &lsquo;G&rsquo; equals &lsquo;C&rsquo; and vice versa.</span></p> <p>*6774497537007713*</p> <p>&nbsp;</p> <h2><strong>Recommendations to Boost Attention</strong></h2> <p>*4494511249520598*</p> <h3><span style="font-weight: 400;">Diet</span></h3> <h4><strong>Eat More Fish</strong></h4> <p><span style="font-weight: 400;">ADHD patients have lower intakes and blood levels of </span><a href="http://selfhacked.com/blog/top-22-science-based-health-benefits-of-fish-oil/"><span style="font-weight: 400;">omega-3</span></a><span style="font-weight: 400;"> fatty acids from fish, which may impair their brain serotonin function [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669464/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562756/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.14-268342"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">For this reason, some health experts suggest increasing fish and seafood intake as a complementary approach to attention disorders [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562756/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Fish oil supplementation has shown promising results for ADHD, but it&rsquo;s unsure whether eating fish would provide similar benefits [</span><a href="http://www.ncbi.nlm.nih.gov/pubmed/11817499"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="http://www.ncbi.nlm.nih.gov/pubmed/18469236"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="http://www.ncbi.nlm.nih.gov/pubmed/17435458"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">Increased fish intake might help prevent attention disorders by targeting your gene variants.</span></p> <h3><strong>Lifestyle</strong></h3> <h4><strong>Improve Sleep Quality</strong></h4> <p><span style="font-weight: 400;">Poor </span><a href="https://selfhacked.com/blog/sleep-neurophysiology/"><span style="font-weight: 400;">sleep</span></a><span style="font-weight: 400;"> quality impairs attention and other cognitive functions [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/12683469"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/15509816/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/3238256/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/9682180/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Chronic sleep deprivation may deplete serotonin and reduce receptor sensitivity [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579986/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Different sleep interventions improved cognitive performance and overall well-being in children with ADHD [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/30654852"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/24957753"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/31184382"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/22005602"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">Improved sleep quality may help lessen the impact of your gene variant on attention.</span></p> <h3><strong>Supplements</strong></h3> <h4><strong>Omega-3</strong></h4> <p><span style="font-weight: 400;">Supplementation with omega-3 fatty acids found in </span><a href="http://selfhacked.com/blog/top-22-science-based-health-benefits-of-fish-oil/"><span style="font-weight: 400;">fish oil</span></a><span style="font-weight: 400;"> (EPA and DHA) improved ADHD symptoms in multiple clinical studies [</span><a href="http://www.ncbi.nlm.nih.gov/pubmed/11817499"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="http://www.ncbi.nlm.nih.gov/pubmed/18469236"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="http://www.ncbi.nlm.nih.gov/pubmed/17435458"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/21807480/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/24958525/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Children receiving omega-3 supplements had their attention, behavior and cognition improved [</span><a href="http://www.ncbi.nlm.nih.gov/pubmed/11817499"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="http://www.ncbi.nlm.nih.gov/pubmed/18469236"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="http://www.ncbi.nlm.nih.gov/pubmed/17435458"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/21807480/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/24958525/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">The benefits of omega-3s for ADHD partly stem from its potential to balance serotonin levels in the brain [</span><a href="https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.14-268342"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">Omega-3 fatty acids may improve ADHD symptoms by targeting your gene variant.</span></p>
323 | content_snp_table_3118695281585939_key == 3118695281585939
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323 | content_learn_more_6774497537007713_key == 6774497537007713
323 | content_learn_more_6774497537007713_blur == True
323 | content_learn_more_6774497537007713_hidden == False
323 | content_learn_more_6774497537007713_text == Based on the variants we looked at, your HTR1B gene is associated with slightly higher odds of ADHD. However, this doesn't necessarily reflect your overall risk of ADHD, just one gene related to it. Proper sleep and higher omega-3 intake may improve ADHD symptoms by targeting your gene variants. Keep reading to learn more.
323 | content_recommendation_4494511249520598_key == 4494511249520598
323 | content_recommendation_4494511249520598_blur == True
323 | content_recommendation_4494511249520598_hidden == False
rsIDs = rs6296
rsStatus = rs6296,HTR1B,chr6,77462543,C,G,,,18,12,HET
