324 | id == 324
324 | category_id == 20
324 | category_order == 17
324 | category_name == Attention
324 | category_color == #C47AC0
324 | slug == DTNBP1-Attention
324 | title == Can This Dopamine Regulating Gene Increase Your Risk Of ADHD? (DTNBP1)
324 | meta_description == DTNBP1 gene variants may be affecting your attention span and ADHD susceptibility. Read on to find out more!
324 | summary == <p style="text-align:justify"><strong><em>DTNBP1</em> variants may influence your attention span. Read on to find out the impact these variants may be having on you and what you can do to reduce it!</strong></p>
324 | overall_score_text == Your Attention Score (based on DTNBP1 gene)
324 | image == https://sd-selfdecode-assets-prod.s3.amazonaws.com/blog/background/DTNBP1-ADHD.jpg
324 | author_id == 13
324 | author_name == Lewis Cuthbertson
324 | author_title == PhD
324 | author_order == 12
324 | author_photo == https://sd-selfdecode-assets-prod.s3.amazonaws.com/blog/author-photo/Lewis_SelfDecode.jpg
324 | author_intro == <p><strong>Lewis completed his PhD in Molecular Microbiology at Northumbria University (UK).</strong></p>    <p>Lewis spent several years researching the biodiversity of bacterial communities in the Arctic and Antarctic, whilst also performing research for a DNA sequencing service, where he was involved in several health based microbiome studies. This gave him an insight into how the highly diverse and invisible to the naked eye portion of human health, can potentially impact an individual&rsquo;s quality of life, driving his desire to help others understand their own complex health needs through the most current scientific research.<br />  &nbsp;</p>
324 | reviewer == None
324 | medical_reviewer_id == 11
324 | medical_reviewer_name == Puya Yazdi
324 | medical_reviewer_title == MD
324 | publish_date == 2020
324 | publish_date == 9
324 | publish_date == 11
324 | avg_rating == 5.0
324 | tags_id == 56
324 | tags_name == Attention
324 | tags_id == 51
324 | tags_name == Dopamine
324 | tags_id == 700
324 | tags_name == DTNBP1 gene
324 | permissions_favorite == False
324 | permissions_rate == False
324 | content_article == <h2 style="text-align: justify;"><span style="font-weight: 400;">Summary</span></h2> <ul style="text-align: justify;"> <li style="font-weight: 400;"><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;"><span style="font-weight: 400;">The </span><a href="../../../gene/dtnbp1/"><em><span style="font-weight: 400;">DTNBP1</span></em></a> <span style="font-weight: 400;">gene encodes dysbindin proteins.</span></span></li> <li style="font-weight: 400;"><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;"><span style="font-weight: 400;">Dysbindin is involved in </span><a href="https://selfhacked.com/blog/dopamine-definition-excess/"><span style="font-weight: 400;">dopamine</span></a><span style="font-weight: 400;"> regulation.</span></span></li> <li style="font-weight: 400;"><span style="font-weight: 400; background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">Gene variants may lower dopamine levels, which can lead to ADHD or poorer attention span.</span></li> </ul> <h2 style="text-align: justify;"><em><span style="font-weight: 400;">DTNBP1</span></em><span style="font-weight: 400;"> and Attention</span></h2> <ul style="text-align: justify;"> <li style="font-weight: 400;"><span style="font-weight: 400;">The </span><em><span style="font-weight: 400;">DTNBP1 </span></em><span style="font-weight: 400;">(Dystrobrevin Binding Protein 1) gene encodes Dysbindin proteins.</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Dysbindin plays a role in the formation of important cell components [</span><a href="https://pubmed.ncbi.nlm.nih.gov/18663367/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Variants of this gene are associated with lower </span><em><span style="font-weight: 400;">DTNBP1</span></em><span style="font-weight: 400;"> expression [</span><a href="https://academic.oup.com/hmg/article/14/14/1947/608349"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Lower </span><em><span style="font-weight: 400;">DTNBP1</span></em><span style="font-weight: 400;"> expression has been shown to influence overall dopamine regulation, and lower dysbindin has also been associated with a large decrease in dopamine [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673263/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/21295953/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Dopamine is associated with reward motivated behaviour. Low dopamine levels are associated with ADHD and poorer attention [</span><a href="https://pubmed.ncbi.nlm.nih.gov/9457173/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">,</span>&nbsp;<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626918/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></li> </ul> <h2 style="text-align: justify;"><span style="font-weight: 400;">Your </span><em><span style="font-weight: 400;">DTNBP1</span></em><span style="font-weight: 400;"> Results for Attention</span></h2> <h3 style="text-align: justify;">*7023476268635265*</h3> <h3 style="text-align: justify;"><span style="font-weight: 400;">SNP Table and Summary</span></h3> <p style="text-align: justify;"><strong>[</strong><strong><em>DTNBP1</em></strong><strong>] rs760761</strong></p> <ul style="text-align: justify;"> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;A&rsquo; = associated with lower attention capacity [</span><a href="https://pubmed.ncbi.nlm.nih.gov/17336946/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/22911901/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;G&rsquo; = not associated with lower attention capacity</span></li> </ul> <p style="text-align: justify;"><strong>[</strong><strong><em>DTNBP1</em></strong><strong>] rs2619522</strong></p> <ul style="text-align: justify;"> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;C&rsquo; = associated with lower attention capacity [</span><a href="https://pubmed.ncbi.nlm.nih.gov/17336946/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;A&rsquo; = not associated with lower attention capacity</span></li> </ul> <p style="text-align: justify;"><strong>[</strong><strong><em>DTNBP1</em></strong><strong>] rs1018381</strong></p> <ul style="text-align: justify;"> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;A&rsquo; = associated with poorer executive control [</span><a href="https://pubmed.ncbi.nlm.nih.gov/20846375/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;G&rsquo; = not associated with poorer executive control</span></li> </ul> <p style="text-align: justify;"><strong>[</strong><strong><em>DTNBP1</em></strong><strong>] rs1011313</strong></p> <ul style="text-align: justify;"> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;T&rsquo; = associated with poorer executive control [</span><a href="https://pubmed.ncbi.nlm.nih.gov/19077176/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;C&rsquo; = not associated with poorer executive control</span></li> </ul> <p style="text-align: justify;"><strong>[</strong><strong><em>DTNBP1</em></strong><strong>] rs2619528</strong></p> <ul style="text-align: justify;"> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;T&rsquo; = associated with poorer executive control [</span><a href="https://pubmed.ncbi.nlm.nih.gov/19077176/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;C&rsquo; = not associated with poorer executive control</span></li> </ul> <p style="text-align: justify;"><strong>*1761107342939243*</strong></p> <h2 style="text-align: justify;"><span style="font-weight: 400;">Recommendations for Improving Attention</span></h2> <p style="text-align: justify;"><strong>*3716519451673026*</strong></p> <h3><span style="font-weight: 400;">Lifestyle</span></h3> <p><a href="https://selfhacked.com/blog/top-14-proven-health-benefits-exercise-references-mechanisms/"><span style="font-weight: 400;">Exercise</span></a><span style="font-weight: 400;"> may increase dopamine levels and is also known to improve overall cognitive performance [</span><a href="https://pubmed.ncbi.nlm.nih.gov/12758062/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/27003115/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928534/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <h3><span style="font-weight: 400;">Diet</span></h3> <p><span style="font-weight: 400;">One of the key ingredients of green tea, </span><a href="https://selfhacked.com/blog/theanine/"><span style="font-weight: 400;">theanine</span></a><span style="font-weight: 400;">, is thought to increase dopamine levels. </span><a href="http://selfhacked.com/blog/green-tea/"><span style="font-weight: 400;">Green tea</span></a><span style="font-weight: 400;"> is also thought to improve cognitive function [</span><a href="https://pubmed.ncbi.nlm.nih.gov/9566605/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/19447283/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/23625424/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/28899506/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <h3><span style="font-weight: 400;">Supplements</span></h3> <p><a href="https://selfhacked.com/blog/8-proven-health-benefits-tyrosine/"><span style="font-weight: 400;">Tyrosine</span></a><span style="font-weight: 400;"> is thought to increase dopamine levels as well as improve general cognitive function [</span><a href="https://pubmed.ncbi.nlm.nih.gov/26424423/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/25598314/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p>
324 | content_snp_table_7023476268635265_key == 7023476268635265
324 | content_snp_table_7023476268635265_blur == True
324 | content_snp_table_7023476268635265_hidden == False
324 | content_learn_more_1761107342939243_key == 1761107342939243
324 | content_learn_more_1761107342939243_blur == True
324 | content_learn_more_1761107342939243_hidden == False
324 | content_learn_more_1761107342939243_text == Based on the variants we looked at, your DTNBP1 gene makes you somewhat more likely to develop a poor attention span. However, this doesn't necessarily reflect your overall risk; it’s just one gene related to it. Keep scrolling to find out more.
324 | content_recommendation_3716519451673026_key == 3716519451673026
324 | content_recommendation_3716519451673026_blur == True
324 | content_recommendation_3716519451673026_hidden == False
rsIDs = rs760761,rs2619522,rs1011313,rs1018381,rs2619528
rsStatus = rs760761,DTNBP1,chr6,15650901,G,A,,,21,0,Normal
rsStatus = rs2619522,DTNBP1,chr6,15653418,A,C,G,,20,0,Normal
rsStatus = rs1011313,DTNBP1,chr6,15633201,T,A,C,,23,0,Normal
rsStatus = rs1018381,DTNBP1,chr6,15656839,G,A,C,T,38,0,Normal
rsStatus = rs2619528,DTNBP1,chr6,15649598,C,T,,,23,0,Normal
