330 | id == 330
330 | category_id == 20
330 | category_order == 17
330 | category_name == Attention
330 | category_color == #C47AC0
330 | slug == TERT-stress-ADHD
330 | title == Genetic Link Between Stress and ADHD (TERT)
330 | meta_description == The TERT gene is crucial for longevity and stress response. Learn about its link with ADHD.
330 | summary == <p style="text-align:justify"><strong>Stress can significantly contribute to ADHD development, depending on one variant in the TERT gene. Read on to check your genes and learn more!</strong></p>
330 | overall_score_text == Your ADHD Score (Based on TERT Gene)
330 | image == https://sd-selfdecode-assets-prod.s3.amazonaws.com/blog/background/TERT-ADHD.jpg
330 | author_id == 9
330 | author_name == Aleksa Ristic
330 | author_title == MS (Pharmacy)
330 | author_order == 45
330 | author_photo == https://sd-selfdecode-assets-prod.s3.amazonaws.com/blog/author-photo/Aleksa.jpg
330 | author_intro == <p><strong>Aleksa received his MS in Pharmacy from the University of Belgrade, his master thesis focusing on protein sources in plant-based diets.</strong>&nbsp;&nbsp;</p>    <p>Aleksa is passionate about herbal pharmacy, nutrition, and functional medicine. He found a way to merge his two biggest passions&mdash;writing and health&mdash;and use them for noble purposes. His mission is to bridge the gap between science and everyday life, helping readers improve their health and feel better.</p>
330 | reviewer == None
330 | medical_reviewer_id == 11
330 | medical_reviewer_name == Puya Yazdi
330 | medical_reviewer_title == MD
330 | publish_date == 2020
330 | publish_date == 9
330 | publish_date == 14
330 | avg_rating == 5.0
330 | tags_id == 30
330 | tags_name == ADHD
330 | tags_id == 56
330 | tags_name == Attention
330 | tags_id == 101
330 | tags_name == Longevity
330 | tags_id == 50
330 | tags_name == Stress
330 | tags_id == 163
330 | tags_name == Telomerase
330 | tags_id == 162
330 | tags_name == Telomeres
330 | tags_id == 161
330 | tags_name == TERT Gene
330 | permissions_favorite == False
330 | permissions_rate == False
330 | content_article == <h2><strong>Summary</strong></h2> <p><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;"><strong>The TERT gene helps counteract stress and aging. </strong><strong>Stress exposure and ADHD symptoms correlate with lower TERT activity.</strong></span><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;"><strong>One gene variant reduces TERT activity and correlates with more severe ADHD.</strong></span><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;"><strong>Specific lifestyle changes may improve attention by targeting your variant.</strong></span></p> <h2><strong>The TERT Gene and ADHD</strong></h2> <p><span style="font-weight: 400;">The </span><a href="https://selfdecode.com/gene/tert/"><span style="font-weight: 400;">TERT</span></a><span style="font-weight: 400;"> gene helps make an enzyme that controls lifespan and response to stress by building </span><a href="https://selfhacked.com/blog/telomerase-telomeres-aging/"><span style="font-weight: 400;">telomeres</span></a><span style="font-weight: 400;"> [</span><a href="https://ghr.nlm.nih.gov/gene/TERT"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Chronic stress exposure lowers TERT activity and shortens telomeres [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/15574496/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/20018236/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Social isolation and ADHD symptoms have been associated with shorter telomeres [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/21577215/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/26217174/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <h2><strong>Your TERT Results for ADHD</strong></h2> <h3>*7099168898812716*</h3> <p><strong>Primary SNP:</strong></p> <p><strong><em>TERT </em></strong><a href="https://selfdecode.com/snp/rs4635969/"><strong>rs4635969</strong></a> <span style="font-weight: 400;">[</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537639/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]:</span></p> <ul> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;A&rsquo; - associated with lower stress tolerance and more severe ADHD</span></li> <li><span style="font-weight: 400;">&lsquo;G&rsquo; - not associated with ADHD or psychological stress</span></li> <li><span style="font-weight: 400;">The &lsquo;A&rsquo; allele may reduce TERT activity.</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Social isolation, bullying, and family issues are more detrimental to ADHD patients with the &lsquo;A&rsquo; allele.</span></li> </ul> <p>*3354209030349016*</p> <h2><strong>Recommendations to Improve Attention</strong></h2> <p>*6802224301455812*</p> <h3><strong>Lifestyle</strong></h3> <h4><strong>Cognitive-Behavioural Therapy</strong></h4> <p><span style="font-weight: 400;">Cognitive-behavioral therapy can reduce stress and help with the social risk factors detrimental to &lsquo;A&rsquo; allele carriers [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/26629933"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633586/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/18091195"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]</span></p> <p><span style="font-weight: 400;">It can improve ADHD symptoms in both adults and adolescents [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/26629933"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633586/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/18091195"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595859/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/24970720"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938293/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155481/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Different forms of behavioral therapy are a part of standard ADHD care &mdash; consult with a healthcare professional about your options.</span></p> <p><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">Cognitive-behavioral therapy may lessen the impact of your gene variants on ADHD development.</span></p> <h4><strong>Exercise</strong></h4> <p><a href="https://selfhacked.com/blog/2016/09/21/top-14-proven-health-benefits-exercise-references-mechanisms/"><span style="font-weight: 400;">Exercise</span></a><span style="font-weight: 400;"> may help reduce stress and extend telomeres by boosting TERT activity [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013452/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994003/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">According to decent clinical evidence, regular exercise may reduce ADHD symptoms [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768113/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372555/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724411/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/21432590"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/20837978"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352161/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675699/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Children and adolescents on different exercise programs saw improvements in attention, behavior, and cognition [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724411/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/21432590"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/20837978"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">Exercise may improve ADHD symptoms by targeting your gene variants.</span></p>
330 | content_snp_table_7099168898812716_key == 7099168898812716
330 | content_snp_table_7099168898812716_blur == True
330 | content_snp_table_7099168898812716_hidden == False
330 | content_learn_more_3354209030349016_key == 3354209030349016
330 | content_learn_more_3354209030349016_blur == True
330 | content_learn_more_3354209030349016_hidden == False
330 | content_learn_more_3354209030349016_text == Based on the variants we looked at, your TERT gene is associated with slightly higher stress levels and ADHD severity. However, this doesn't necessarily reflect your overall risk of ADHD, just one gene related to it. Regular exercise may improve ADHD symptoms by targeting your gene variants. Keep reading to learn more.
330 | content_recommendation_6802224301455812_key == 6802224301455812
330 | content_recommendation_6802224301455812_blur == True
330 | content_recommendation_6802224301455812_hidden == False
rsIDs = rs4635969
rsStatus = rs4635969,,chr5,1308437,G,A,T,,23,0,Normal
