350 | id == 350
350 | category_id == 21
350 | category_order == 18
350 | category_name == Anxiety
350 | category_color == #C47AC0
350 | slug == FAAH-cannabinoids-anxiety
350 | title == Genetic Link Between Cannabinoids & Anxiety (FAAH)
350 | meta_description == The FAAH gene influences your cannabinoid system. Click to learn about its link with stress & anxiety.
350 | summary == <p style="text-align:justify"><strong>Cannabinoids are essential for mental health and stress reduction! Read this post to learn the link between the FAAH gene, cannabinoid system, and anxiety.</strong></p>
350 | overall_score_text == Your Anxiety Score (Based on FAAH Gene)
350 | image == https://sd-selfdecode-assets-prod.s3.amazonaws.com/blog/background/FAAH-Anxiety.jpg
350 | author_id == 9
350 | author_name == Aleksa Ristic
350 | author_title == MS (Pharmacy)
350 | author_order == 45
350 | author_photo == https://sd-selfdecode-assets-prod.s3.amazonaws.com/blog/author-photo/Aleksa.jpg
350 | author_intro == <p><strong>Aleksa received his MS in Pharmacy from the University of Belgrade, his master thesis focusing on protein sources in plant-based diets.</strong>&nbsp;&nbsp;</p>    <p>Aleksa is passionate about herbal pharmacy, nutrition, and functional medicine. He found a way to merge his two biggest passions&mdash;writing and health&mdash;and use them for noble purposes. His mission is to bridge the gap between science and everyday life, helping readers improve their health and feel better.</p>
350 | reviewer == None
350 | medical_reviewer_id == 11
350 | medical_reviewer_name == Puya Yazdi
350 | medical_reviewer_title == MD
350 | publish_date == 2020
350 | publish_date == 9
350 | publish_date == 24
350 | avg_rating == 5.0
350 | tags_id == 660
350 | tags_name == Anandamide
350 | tags_id == 112
350 | tags_name == Anxiety
350 | tags_id == 692
350 | tags_name == Cannabinoids
350 | tags_id == 370
350 | tags_name == FAAH Gene
350 | tags_id == 50
350 | tags_name == Stress
350 | permissions_favorite == False
350 | permissions_rate == False
350 | content_article == <h2><strong>Summary</strong></h2> <p><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;"><strong>The </strong><strong><em>FAAH</em></strong><strong> gene helps break down anandamide, a cannabinoid that reduces stress and anxiety. Less FAAH = more anandamide = less anxiety.</strong></span><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;"><strong>One gene variant can impact stress response and anxiety by changing FAAH activity.</strong></span><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;"><strong>Specific lifestyle changes and supplements may help reduce anxiety by targeting the </strong><strong><em>FAAH</em></strong><strong> gene.</strong></span></p> <h2><strong>The FAAH Gene, Cannabinoids &amp; Anxiety</strong></h2> <p><span style="font-weight: 400;">The </span><a href="http://selfhacked.com/blog/the-bliss-gene-faah-snps-rs324420/"><em><span style="font-weight: 400;">FAAH</span></em></a><span style="font-weight: 400;"> gene encodes an enzyme that breaks down the main internal </span><a href="https://selfhacked.com/blog/49-ways-increase-natural-cannabinoids-without-smoking-pot-including-ways-decrease-cannabinoids/"><span style="font-weight: 400;">cannabinoid</span></a><span style="font-weight: 400;">, anandamide [</span><a href="https://ghr.nlm.nih.gov/gene/FAAH"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Anandamide activates cannabinoid receptors and reduces </span><a href="https://selfhacked.com/blog/natural-treatments-anxiety/"><span style="font-weight: 400;">anxiety</span></a><span style="font-weight: 400;">. Increasing anandamide levels may help with both acute and chronic anxiety [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/25004388/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/22776900/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Scientists are developing FAAH enzyme inhibitors as potential anti-anxiety drugs [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917016/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/28234213/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><a href="https://selfhack.com/blog/the-bliss-gene-faah-snps-rs324420/"><span style="font-weight: 400;">Read this post</span></a><span style="font-weight: 400;"> to learn more about the impact of </span><em><span style="font-weight: 400;">FAAH</span></em><span style="font-weight: 400;"> on mental health, obesity, and more.</span></p> <p><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">The FAAH gene impacts the levels of anandamide, an internal cannabinoid that reduces anxiety.</span></p> <h2><strong>Your FAAH Results for Anxiety</strong></h2> <p>*7859607153827488*</p> <p><strong><em>FAAH</em></strong> <a href="../../../snp/rs324420/"><strong>rs324420</strong></a> <span style="font-weight: 400;">[</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748341/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]:</span></p> <ul> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;A&rsquo; - associated with lower anxiety in response to stress</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;C&rsquo; - associated with relatively higher anxiety in response to stress</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">The &lsquo;A&rsquo; allele reduces FAAH activity and increases anandamide.</span></li> </ul> <p>*1357518760047062*</p> <p>&nbsp;</p> <h2><strong>Recommendations to Relieve Anxiety</strong></h2> <p>*9731678303164353*</p> <h3><strong>Lifestyle</strong></h3> <h4><strong>Relaxation Techniques</strong></h4> <p><a href="https://selfhacked.com/blog/63-factors-raising-stress-cortisol-level-backed-science/"><span style="font-weight: 400;">Stress</span></a><span style="font-weight: 400;"> can enhance</span><em><span style="font-weight: 400;"> FAAH</span></em><span style="font-weight: 400;"> gene expression and enzyme activity [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348185/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/25083571/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]. Additionally, chronic stress inhibits main cannabinoid receptors (CB1), leading to lower </span><a href="https://selfhacked.com/blog/49-ways-increase-natural-cannabinoids-without-smoking-pot-including-ways-decrease-cannabinoids/"><span style="font-weight: 400;">cannabinoid</span></a><span style="font-weight: 400;"> function [</span><a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706194/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">For this reason, people with higher FAAH activity have higher </span><a href="https://selfhacked.com/blog/natural-treatments-anxiety/"><span style="font-weight: 400;">anxiety</span></a><span style="font-weight: 400;"> levels in response to stress [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748341/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Different relaxation techniques can reduce stress and help with anxiety:</span></p> <ul> <li style="font-weight: 400;"><span style="font-weight: 400;">Mindfulness [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837056/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0063263/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Applied relaxation [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783580/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/19218829"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/10937426"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]</span></li> <li style="font-weight: 400;"><a href="https://selfhacked.com/blog/health-benefits-yoga/"><span style="font-weight: 400;">Yoga</span></a><span style="font-weight: 400;"> [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/26228429"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111147/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="http://journals.sagepub.com/doi/abs/10.2466/pms.109.3.924-930"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/19341989"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]</span></li> <li style="font-weight: 400;"><a href="https://selfhacked.com/blog/massage-health-benefits/"><span style="font-weight: 400;">Massage</span></a><span style="font-weight: 400;"> [</span><a href="https://pubmed.ncbi.nlm.nih.gov/28750965/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/29173797"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]</span></li> </ul> <p><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">Reducing stress with your favorite relaxation techniques may help relieve anxiety by targeting your <em>FAAH</em> gene.</span></p> <h3><strong>Supplements</strong></h3> <h4><strong>CBD Oil</strong></h4> <p><a href="https://selfhacked.com/blog/cannabidiol-cbd/"><span style="font-weight: 400;">CBD</span></a><span style="font-weight: 400;">, the active ingredient in cannabis and hemp, can inhibit the FAAH enzyme [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573017/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/28120232/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">CBD reduced anxiety from stressful situations such as public speaking and medical procedures in several trials on healthy people [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/14583744"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/22290374"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">,</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425583/"> <span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">,</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/30328956"> <span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">According to preliminary evidence, it may help with various anxiety disorders, including social anxiety and panic disorders </span><span style="font-weight: 400;">[</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326553/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">,</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101100/"> <span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">,</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/6285406"> <span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/31866386/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856203/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412699/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Note that CBD oil is derived from </span><a href="https://selfhacked.com/blog/top-6-unique-super-effective-ways-counteract-negative-performance-effects-cannabismarijuana/?utm_source=seo&amp;#38;utm_medium=selfhacked&amp;#38;utm_campaign=id00002"><span style="font-weight: 400;">cannabis</span></a><span style="font-weight: 400;">, which is a controlled substance in many countries and states. Therefore, make sure to verify the legality of CBD products where you live before seeking them out.</span></p> <p><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">CBD oil may reduce the impact of your FAAH gene on stress and anxiety.</span></p>
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350 | content_learn_more_1357518760047062_text == Based on the variant we looked at, your FAAH gene is associated with relatively higher odds of anxiety. However, this doesn't necessarily reflect your overall risk of anxiety, just one gene related to it. Relaxation techniques and CBD oil may improve anxiety symptoms by targeting your gene variant. Keep reading to learn more.
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rsIDs = rs324420
rsStatus = rs324420,FAAH,chr1,46405089,C,A,,,20,13,HET
