577 | id == 577
577 | category_id == 30
577 | category_order == 27
577 | category_name == Hair Loss
577 | category_color == #C47AC0
577 | slug == SYF2-cell-cycle-baldness
577 | title == Potential Link Between Cell Cycle Control & Hair Growth (SYF2)
577 | meta_description == The SYF2 gene may support hair growth by preventing the death of hair follicle cells. Click to check your variants.
577 | summary == <p style="text-align:justify"><strong>The cell cycle function in the hair follicle may have a crucial impact on hair growth. Read this post to learn about the link between the <em>SYF2</em> gene and male-pattern baldness &mdash; personalized tips included!</strong></p>
577 | overall_score_text == Your male-pattern baldness Score (based on SYF2 gene)
577 | image == https://sd-selfdecode-assets-prod.s3.amazonaws.com/blog/background/SYF2-Male-pattern-baldness.jpg
577 | author_id == 9
577 | author_name == Aleksa Ristic
577 | author_title == MS (Pharmacy)
577 | author_order == 45
577 | author_photo == https://sd-selfdecode-assets-prod.s3.amazonaws.com/blog/author-photo/Aleksa.jpg
577 | author_intro == <p><strong>Aleksa received his MS in Pharmacy from the University of Belgrade, his master thesis focusing on protein sources in plant-based diets.</strong>&nbsp;&nbsp;</p>    <p>Aleksa is passionate about herbal pharmacy, nutrition, and functional medicine. He found a way to merge his two biggest passions&mdash;writing and health&mdash;and use them for noble purposes. His mission is to bridge the gap between science and everyday life, helping readers improve their health and feel better.</p>
577 | reviewer == None
577 | medical_reviewer_id == 11
577 | medical_reviewer_name == Puya Yazdi
577 | medical_reviewer_title == MD
577 | publish_date == 2020
577 | publish_date == 12
577 | publish_date == 29
577 | avg_rating == 5.0
577 | tags_id == 1087
577 | tags_name == Cell Cycle
577 | tags_id == 768
577 | tags_name == Cell Death
577 | tags_id == 1032
577 | tags_name == Hair Follicle
577 | tags_id == 1058
577 | tags_name == Hair Growth
577 | tags_id == 1028
577 | tags_name == Male-Pattern Baldness
577 | tags_id == 1088
577 | tags_name == SYF2 gene
577 | permissions_favorite == False
577 | permissions_rate == False
577 | content_article == <h2><strong>Summary</strong></h2> <p><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;"><strong>The </strong><strong><em>SYF2</em></strong><strong> gene may support hair growth by preventing the death of hair follicle cells.<br /><br /></strong><strong>Specific gene variants may reduce SYF2 activity. They&rsquo;ve been associated with relatively higher odds of male-pattern baldness.<br /><br /></strong><strong>This post reveals two simple ways to stimulate hair growth by targeting your gene variants.</strong></span></p> <p>&nbsp;</p> <h2><strong>The SYF2 Gene &amp; Hair Growth</strong></h2> <p><span style="font-weight: 400;">The </span><a href="https://selfdecode.com/gene/syf2/"><em><span style="font-weight: 400;">SYF2</span></em></a><span style="font-weight: 400;"> gene helps make a protein that regulates the cell cycle; increased activity of this gene enhances cell division [</span><a href="https://www.ncbi.nlm.nih.gov/gene/25949"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">So far, researchers have studied the role of SYF2 in cancer cell division. We are still to learn about its role in hair growth, but it likely supports this process by preventing the death of hair follicle cells [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687618/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">The SYF2 gene may support hair growth by preventing the death of hair follicle cells.</span></p> <p>&nbsp;</p> <h2><strong>Your SYF2 Results for Male-Pattern Baldness</strong></h2> <p>*5034056610015922*</p> <p><strong>Primary SNP:</strong></p> <p><a href="https://selfdecode.com/snp/rs2064251/"><strong>rs2064251</strong></a> <span style="font-weight: 400;">[</span><a href="https://pubmed.ncbi.nlm.nih.gov/25826379/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691155/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]:</span></p> <ul> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;A&rsquo; - associated with relatively higher odds of male-pattern baldness</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;G&rsquo; - associated relatively lower odds of male-pattern baldness</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">The &lsquo;A&rsquo; allele likely reduces SYF2 activity and promotes cell death in the hair follicle.</span></li> </ul> <p><strong>Another Important SNP:</strong></p> <p><a href="https://selfdecode.com/snp/rs7534070/"><strong>rs7534070</strong></a> <span style="font-weight: 400;">[</span><a href="https://pubmed.ncbi.nlm.nih.gov/25826379/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207801/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.nature.com/articles/ncomms14694"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]:</span></p> <ul> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;G&rsquo; - associated with relatively higher odds of male-pattern baldness</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;T&rsquo; - associated relatively lower odds of male-pattern baldness</span></li> </ul> <p>*8205143988532817*</p> <p>&nbsp;</p> <h2><strong>Recommendations to Stimulate Hair Growth</strong></h2> <p>*8276298075501681*</p> <h3><strong>Topical Caffeine</strong></h3> <p><span style="font-weight: 400;">Topical </span><a href="https://selfhacked.com/blog/caffeine-benefits/"><span style="font-weight: 400;">caffeine</span></a><span style="font-weight: 400;"> application may reduce the death rate of hair follicle cells by boosting their metabolism [<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500065/">R</a>].</span></p> <p><span style="font-weight: 400;">Lotions and shampoos with caffeine increased hair strength and thickness in four trials of men with male-pattern baldness. In one study, a shampoo with caffeine used for 6 months reduced hair loss in women [</span><a href="http://iscd.it/files/Use-of-a-Cosmetic-Caffeine-Lotion-in-the-Treatment-of-Male-Androgenetic-Alopecia.pdf"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="http://www.iscd.it/files/Use-of-a-Caffeine-Shampoo-for-the-Treatment-of-Male-Androgenetic-Alopecia.pdf"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="http://jmums.mazums.ac.ir/article-1-1689-en.html"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804833/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/29512972/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">Topical caffeine may promote hair growth by targeting your gene variants.</span></p> <h3><strong>Topical L-Carnitine</strong></h3> <p><span style="font-weight: 400;">A topical solution with 2% </span><a href="https://selfhacked.com/blog/carnitine-top-18-science-based-health-effects-carnitine/"><span style="font-weight: 400;">L-carnitine</span></a><span style="font-weight: 400;"> (applied for six months) increased hair density and stimulated hair growth in one study. L-carnitine promoted hair follicle cell growth while preventing their death [</span><a href="https://pubmed.ncbi.nlm.nih.gov/17804203/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://pubmed.ncbi.nlm.nih.gov/17927577/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Two similar solutions with L-carnitine, </span><a href="https://selfhacked.com/blog/gamma-linolenic-acid/"><span style="font-weight: 400;">gamma-linolenic acid</span></a><span style="font-weight: 400;">, and a compound from soybean (equol) may boost hair growth after 1-6 months of application [</span><a href="https://pubmed.ncbi.nlm.nih.gov/30371981/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="background-color: #e8ebfc; border-left: 2px solid #4569fa; display: block; padding: 20px;">Topical solutions with L-carnitine may lessen the impact of your SYF2 variants and reduce hair loss.</span></p>
577 | content_snp_table_5034056610015922_key == 5034056610015922
577 | content_snp_table_5034056610015922_blur == True
577 | content_snp_table_5034056610015922_hidden == False
577 | content_learn_more_8205143988532817_key == 8205143988532817
577 | content_learn_more_8205143988532817_blur == True
577 | content_learn_more_8205143988532817_hidden == False
577 | content_learn_more_8205143988532817_text == Based on the variants we looked at, your SYF2 gene is associated with relatively higher odds of male-pattern baldness. However, this doesn't necessarily reflect your overall risk of male-pattern baldness; it’s just one gene related to it. Topical caffeine and L-carnitine may promote hair growth by targeting your variant. Keep scrolling to find out more.
577 | content_recommendation_8276298075501681_key == 8276298075501681
577 | content_recommendation_8276298075501681_blur == True
577 | content_recommendation_8276298075501681_hidden == False
rsIDs = rs2064251,rs7534070
rsStatus = rs2064251,,chr1,25143422,G,A,,,13,7,HET
rsStatus = rs7534070,,chr1,25171684,G,A,T,,32,0,Normal
