90 | id == 90
90 | category_id == 9
90 | category_order == 6
90 | category_name == Longevity
90 | category_color == #C47AC0
90 | slug == PPARD-Longevity
90 | title == How A Fat Metabolism Gene Affects Longevity (PPARD)
90 | meta_description == The PPARD gene plays a major role in fat metabolism, while also potentially influencing longevity. Find out more here!
90 | summary == <p style="text-align:justify"><strong>The PPARD gene helps regulate many systems in the body, including fat metabolism, insulin production, and inflammation. According to research, certain variants in PPARD may also be linked to longer lifespans. Find out how this gene works and how it affects longevity.</strong></p>
90 | overall_score_text == Your Longevity Score (Based On PPARD gene)
90 | image == https://sd-selfdecode-assets-prod.s3.amazonaws.com/blog/background/PPARD--Longevity.jpg
90 | author_id == 8
90 | author_name == Mathew Eng
90 | author_title == PharmD
90 | author_order == 40
90 | author_photo == https://sd-selfdecode-assets-prod.s3.amazonaws.com/blog/author-photo/Mathew.jpg
90 | author_intro == <p><strong>Mathew received his PharmD from the University of Hawaii and an undergraduate degree in Biology from the University of Washington.</strong></p>    <p>Mathew is a licensed pharmacist with clinical experience in oncology, infectious disease, and diabetes management. He has a passion for personalized patient care and believes that education is essential to living a healthy life. His goal is to motivate individuals to find ways to manage their chronic conditions.</p>
90 | reviewer == None
90 | medical_reviewer_id == 11
90 | medical_reviewer_name == Puya Yazdi
90 | medical_reviewer_title == MD
90 | publish_date == 2020
90 | publish_date == 2
90 | publish_date == 5
90 | avg_rating == 5.0
90 | tags_id == 24
90 | tags_name == Inflammation
90 | tags_id == 139
90 | tags_name == Insulin
90 | tags_id == 116
90 | tags_name == Insulin Resistance
90 | tags_id == 101
90 | tags_name == Longevity
90 | tags_id == 140
90 | tags_name == Metabolism
90 | tags_id == 241
90 | tags_name == PPARD gene
90 | permissions_favorite == False
90 | permissions_rate == False
90 | content_article == <table style="width: 90%; border-collapse: collapse; margin-left: auto; margin-right: auto;" border="1" cellpadding="10"> <tbody> <tr> <td style="width: 100%;"><span style="font-weight: 400;"><strong>Note:</strong> The </span><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;"> gene is mentioned in the </span><a href="https://get.selfdecode.com/gene-reports/fitness/"><span style="font-weight: 400;">Fitness DNA Wellness Report</span></a><span style="font-weight: 400;">, along with many other genes. If you're looking for a comprehensive report on how your genes may influence your response to exercise and injury, check it out!</span></td> </tr> </tbody> </table> <p>&nbsp;</p> <h2><strong>What Is The <em>PPARD</em> Gene?</strong></h2> <p><span style="font-weight: 400;">The </span><a href="../../gene/ppard/"><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;"> gene</span></a><span style="font-weight: 400;"> is responsible for encoding a protein called </span><strong>PPAR-&delta;</strong><span style="font-weight: 400;"> (also sometimes known as PPAR-&beta; or NR1C2) [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255347/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">The PPAR-&delta; protein is involved in several processes in the body, some of which include [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255347/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275063/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]:</span></p> <ul> <li style="font-weight: 400;"><span style="font-weight: 400;">Metabolism of fat</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Controlling </span><a href="https://selfhacked.com/blog/natural-ways-lower-inflammation/"><span style="font-weight: 400;">inflammation</span></a></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Regulating </span><a href="https://selfhacked.com/blog/insulin-101/"><span style="font-weight: 400;">insulin</span></a><span style="font-weight: 400;"> activity</span></li> </ul> <p><span style="font-weight: 400;">Research suggests that certain genetic variants of </span><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;"> may be associated with various health conditions, such as high </span><a href="https://www.selfhacked.com/blog/cholesterol/"><span style="font-weight: 400;">cholesterol</span></a><span style="font-weight: 400;">, obesity, and high blood pressure [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/18288282"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/22968028"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/23937834"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Interestingly enough, there is also some evidence that certain variants of </span><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;"> may even be linked to </span><a href="https://selfhacked.com/blog/lifestyle-diet-increase-longevity/"><span style="font-weight: 400;">longer lifespans</span></a><span style="font-weight: 400;"> [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356147/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/23186209"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <h3><strong>The PPAR-&delta; Protein</strong></h3> <p><span style="font-weight: 400;">The PPAR-&delta; protein is created with help from the </span><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;"> gene. This protein can be found throughout the body, including the muscles, lungs, brain, and skin [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255347/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275063/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">As mentioned earlier, PPAR-&delta; has various functions in the body, such as metabolizing fatty acids, suppressing inflammatory compounds, and regulating insulin production [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255347/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275063/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">PPAR-&delta; primarily works by regulating the expression of other genes. Here&rsquo;s an example of how it helps metabolize fat [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275063/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]:</span></p> <ol> <li style="font-weight: 400;"><span style="font-weight: 400;">Fatty acid molecules (the basic form of fat) attach to PPAR-&delta;</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Once bounded, PPAR-&delta; promotes the expression of genes involved in fat metabolism</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">These newly activated genes produce proteins that play a role in fat transport, fat breakdown, and the conversion of fat to energy</span></li> </ol> <p><span style="font-weight: 400;">PPAR-&delta; exerts its other effects through a similar process. Many different molecules can bind to PPAR-&delta; and it is able to target several different genes, leading to a number of distinct effects [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275063/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <h2><strong>How Does <em>PPARD</em> Affect Lifespan</strong></h2> <p><span style="font-weight: 400;">So far, we&rsquo;ve discussed how the </span><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;"> gene plays several roles in the body, including fat metabolism, inflammation control, and insulin production.</span></p> <p><span style="font-weight: 400;">But how exactly does </span><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;"> affect lifespan? The answer is complex and not yet fully understood.</span></p> <p><span style="font-weight: 400;">According to some researchers, </span><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;"> may be able to improve longevity by counteracting some of the processes seen in aging [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254525/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">For example, as humans age, the body naturally shifts from using fats as the preferred energy source to using carbohydrates. The </span><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;"> gene counteracts this shift by promoting the use of fat as energy [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254525/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">By improving fat metabolism, </span><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;"> may increase longevity by preventing health disorders related to increased body fat [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254525/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><a href="https://selfhacked.com/blog/oxidative-stress-101/"><span style="font-weight: 400;">Oxidative stress</span></a><span style="font-weight: 400;"> related to inflammation and </span><a href="https://www.selfhacked.com/blog/top-tips-for-fixing-insulin-resistance/"><span style="font-weight: 400;">insulin resistance</span></a><span style="font-weight: 400;"> also increase with age. Activation of </span><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;"> can potentially counteract these processes, which may also contribute to longer lifespans [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254525/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <h2><strong><em>PPARD</em> And Longevity</strong></h2> <p><span style="font-weight: 400;">There is some evidence that certain variants in the </span><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;"> gene are associated with </span><a href="https://selfhacked.com/blog/lifestyle-diet-increase-longevity/"><span style="font-weight: 400;">longevity</span></a><span style="font-weight: 400;">.</span></p> <p><span style="font-weight: 400;">More specifically, a variation in </span><a href="../../snp/rs2016520/"><span style="font-weight: 400;">rs2016520</span></a><span style="font-weight: 400;"> (also known as </span><em><span style="font-weight: 400;">PPARD </span></em><span style="font-weight: 400;">+294T/C) was found to be significantly more common in those that live exceptionally long lives [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356147/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">According to a study of nearly 1,000 Chinese people originating from a region called Bama,</span><strong> the &lsquo;T&rsquo; allele is more frequently found in those aged 90 and above</strong><span style="font-weight: 400;">. However, this association was only present in women [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356147/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Interestingly enough, long-lived individuals also had significantly </span><em><span style="font-weight: 400;">higher</span></em> <a href="https://selfhacked.com/blog/cholesterol/"><span style="font-weight: 400;">cholesterol</span></a><span style="font-weight: 400;"> and </span><a href="https://selfhacked.com/blog/triglycerides/"><span style="font-weight: 400;">triglyceride</span></a><span style="font-weight: 400;"> (fat) levels compared to younger subjects.</span></p> <p><span style="font-weight: 400;">This suggests that the effect of rs2016520 on lifespan may not be linked to fat metabolism and may involve other factors instead [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356147/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <h2><strong>Your <em>PPARD</em> Results for Longevity</strong></h2> <p><em><span style="font-weight: 400;">You can see your genotypes for PPARD in the table below. However, keep in mind that these associations are based on studies from certain ethnic populations &mdash; so you should interpret your results with caution if you are not descended from one of these specific groups!</span></em></p> <p>*3791020049413811*</p> <p><strong>Primary SNP:&nbsp;</strong></p> <p><strong>PPARD </strong><a href="../../snp/rs2016520/"><strong>rs2016520</strong></a></p> <ul> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;C&rsquo; = No association with longevity</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">&lsquo;T&rsquo; = More common in those with longer lifespans in certain populations</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">The association between the &lsquo;T&rsquo; allele and longevity has only been found in women from certain Chinese populations</span></li> </ul> <p>*3939582312822047*</p> <h3><strong>Frequency in Population</strong></h3> <p><span style="font-weight: 400;">Generally speaking, the &lsquo;T&rsquo; allele is much more common than the &lsquo;C&rsquo; allele.&nbsp;</span></p> <p><span style="font-weight: 400;">About 96% of Europeans carry at least one &lsquo;T&rsquo; allele. </span></p> <p><span style="font-weight: 400;">In Asian populations, about 94% carry at least one &lsquo;T&rsquo; allele. </span></p> <p><span style="font-weight: 400;">The frequency of the &lsquo;T&rsquo; allele is similar in other ethnicities.</span></p> <h2><strong>Recommendations For Longevity</strong></h2> <p><em><span style="font-weight: 400;">Before implementing any of the following strategies, always speak with your doctor first about your options! There may be unexpected interactions with your current medications or health conditions.&nbsp;</span></em></p> <p><em><span style="font-weight: 400;">Also keep in mind that none of these recommendations should ever be used to replace any of the treatments or medications that your doctor gives you.</span></em></p> <h3><strong>How Do These Recommendations Help With Longevity?</strong></h3> <p><span style="font-weight: 400;">It&rsquo;s not totally clear how the </span><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;"> gene affects longevity. There is conflicting evidence on how variants in rs2016520 impact health.</span></p> <p><span style="font-weight: 400;">On the one hand, the &lsquo;C&rsquo; allele (the allele </span><em><span style="font-weight: 400;">not</span></em><span style="font-weight: 400;"> associated with longevity) has been connected to negative effects on lifespan, such as higher cholesterol levels [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/12615676"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233806/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">On the other hand, the &lsquo;C&rsquo; allele has also been linked to positive outcomes, such as lower risk of obesity and better athletic performance [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/22968028"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/18240567"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">In addition, there is evidence that the rare &lsquo;C&rsquo; allele </span><em><span style="font-weight: 400;">increases</span></em><span style="font-weight: 400;"> the activity of </span><em><span style="font-weight: 400;">PPARD </span></em><span style="font-weight: 400;">[</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/12615676"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/18240567"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Because it&rsquo;s unclear how </span><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;"> activity affects longevity, the following recommendations will focus on general strategies that have been shown to improve longevity (instead of methods that directly change the activity of the </span><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;"> gene).</span></p> <p>*2258635503300423*</p> <h3><strong>Lifestyle</strong></h3> <h4><strong>Regular Physical Activity</strong></h4> <p><a href="https://selfhacked.com/blog/top-14-proven-health-benefits-exercise-references-mechanisms/"><span style="font-weight: 400;">Exercise</span></a><span style="font-weight: 400;"> produces many of the same beneficial health effects that have been linked to </span><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;">.</span></p> <p><span style="font-weight: 400;">For example, regular physical activity is an effective way to reduce cholesterol and triglyceride (fat) levels in the blood, according to strong clinical research [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906547/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Studies also show that consistent aerobic exercise reduces the risk of insulin resistance [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569266/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Interestingly enough, PPAR-&delta; is found in muscle and expression of </span><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;"> is increased after exercise, leading to an increase in muscle fibers [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419664/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Regardless of the relationship between exercise and the </span><em><span style="font-weight: 400;">PPARD </span></em><span style="font-weight: 400;">gene, regular physical activity has consistently been shown to be one of the best ways to extend lifespan and improve quality of life [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/23063021"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/28943267"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501820/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <h4><strong>Managing Weight</strong></h4> <p><span style="font-weight: 400;">The </span><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;"> gene plays a key role in the transportation and metabolization of triglycerides (the most common type of fat in the body). However, it&rsquo;s not exactly clear how this relationship affects longevity [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/18288277"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">What is clear is that bodyweight has a significant impact on lifespan. According to some estimates, obesity may reduce life expectancy by 10 years or more [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/30283076"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">There is also evidence that high amounts of body fat can accelerate the aging process and increase the risk of age-related disease [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/26846415"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><a href="https://selfhacked.com/blog/ways-to-lose-weight-fast/"><span style="font-weight: 400;">Restoring body weight</span></a><span style="font-weight: 400;"> to a normal BMI can reverse these negative effects and potentially improve longevity [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115619/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <h4><strong>Quitting smoking</strong></h4> <p><span style="font-weight: 400;">There&rsquo;s evidence that smoking can increase cholesterol and triglyceride levels, which can contribute to the risk of cardiovascular disease. Quitting can help restore these levels to normal [</span><a href="https://www.cdc.gov/tobacco/campaign/tips/diseases/heart-disease-stroke.html"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">There is also an interesting interaction between </span><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;"> and smoking. One study suggests that the risk of cardiovascular disease may change depending on the rs2016520 genotype and smoking status [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/28287878"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">In any case, smoking is one of the leading causes of preventable death in the world. For smokers, quitting can significantly improve life expectancy [</span><a href="https://www.cdc.gov/tobacco/data_statistics/fact_sheets/health_effects/tobacco_related_mortality/index.htm"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <h3><strong>Diet</strong></h3> <p><span style="font-weight: 400;">The </span><em><span style="font-weight: 400;">PPARD</span></em><span style="font-weight: 400;"> gene plays a key role in fat metabolism and animal studies show that high-fat diets can increase the activity of PPAR-&delta;, although it&rsquo;s uncertain how this plays into longevity [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275063/"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">What is certain is that certain food choices can help reduce cholesterol, reduce triglyceride levels, and potentially improve longevity. These recommendations include [</span><a href="https://www.ncbi.nlm.nih.gov/pubmed/30060746"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">, </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/30401007"><span style="font-weight: 400;">R</span></a><span style="font-weight: 400;">]:</span></p> <ul> <li style="font-weight: 400;"><span style="font-weight: 400;">Reducing the amount of saturated and trans fats in the diet</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Eating more fruits and vegetables</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Eating more fish and other seafood</span></li> <li style="font-weight: 400;"><span style="font-weight: 400;">Trying the Mediterranean diet</span></li> </ul>
90 | content_snp_table_3791020049413811_key == 3791020049413811
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90 | content_snp_table_3791020049413811_hidden == False
90 | content_learn_more_3939582312822047_key == 3939582312822047
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90 | content_learn_more_3939582312822047_text == Based on the variants we looked at, your PPARD genotype is somewhat associated with longevity in certain ethnic groups. However, this doesn't necessarily reflect your overall longevity — just one gene related to it. Lifestyle and diet changes can help. Keep scrolling to find out more.
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rsIDs = rs2016520
rsStatus = rs2016520,PPARD,chr6,35411001,C,A,T,,38,0,Normal
